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Epidemiological research of MP pneumonia and you may RWE away from 2003 so you can 2014

Epidemiological research of MP pneumonia and you may RWE away from 2003 so you can 2014

Analytical studies

All calculations were performed with SPSS V.14.0 (SPSS Inc.)parisons between groups were performed using the Student’s t-test, ? 2 test and Fisher’s exact test, and the data were expressed as mean±SD for continuous variables. A p value of <0.05 was considered statistically significant.

Results

The subjects in the modern studies had been 793 customers which have MP pneumonia and 384 patients that have RWE into the research several months. To own epidemiological assessment, an entire 793 people were used, as found during the before had written article.fourteen Getting scientific testing amongst the organizations, all in all, 501 MP pneumonia people that have been admitted while in the the brand new latest epidemics (241 times when you look at the 2007–2006, and you may 260 cases last year), and you will 384 clients having RWE was in fact analysed (profile step one). Within the investigation months, the full level of accepted patients at our service is a good complete twenty-five 911 (except nursery patients). There were around 2100 acknowledge customers annually with differences in the every year.

A lot of MP pneumonia clients got realize-right up period no less than www.datingranking.net/pl/fabswingers-recenzja/ 3 years away from past epidemic seasons from 2011, although pursue-right up subjects happy with our selection standards was basically 180 among 501 cases from the MP pneumonia classification and you will 206 certainly 384 cases throughout the RWE classification.

In the MP pneumonia customers, there have been clear episodes out-of instances into the 2003, 2006–2007 and you will 2011, with many cases taking place about interepidemic attacks. There have been seemingly regular amounts of RWE instances each year through the the analysis months. There have been zero corresponding improved cases within the MP pneumonia crisis ages but in 2007 (figure dos). No MP pneumonia diligent who had been readmitted due to MP reinfection along side epidemics are seen throughout analysis months. The brand new imply many years and you can decades shipments was basically similar, and height age range was in fact dos–5 years old in teams (figure 3). From inside the seasonality off both groups, MP pneumonia is commonplace inside the decreasing order out of autumn, summer, winter and you may spring, while you are patients with RWE have been extremely prevalent in the fall, followed by springtime, winter and you will summer (analysis maybe not shown).

Demographic and scientific attributes of MP pneumonia and you can RWE organizations

Demographic, clinical and laboratory data in both groups are shown in table 1. The mean age and age distribution were similar in both groups as shown in figure 3 (5.4 years vs 5.6 years, p=0.312). Both groups had male predominance, and there were more males in the RWE group. As expected, cases with wheezing at presentation, the proportion of patients with history or family history of allergic diseases, and history of wheezing were higher in the RWE group. Recurrent wheezing after discharge was observed in 38 of 180 patients with MP pneumonia and 141 of the 206 patients with RWE (p<0.001).

In MP pneumonia patients, 52 of the total 501 patients (10.4%) had wheezing at presentation, 72 (14.4%) had a history of allergic diseases, 15 (3%) had RWE according to our definition and 40 (8%) had a family history of allergic diseases. When we divided the MP pneumonia patients into two groups of patients with wheezing (n=52) and without wheezing (n=449), the patients with wheezing were younger (3.7 years vs 5.6 years, p<0.001) and had higher proportions of history allergic diseases and wheezing history and higher values of leucocyte count and eosinophil differential (table 2). Among the 52 MP pneumonia patients with wheezing at admission, 10 were patient with RWE, while 42 had no previous RWE history. Thus, in this study, 66% (10 of 15) of patients with RWE history presented with wheezing, while 8.6% of patients without RWE history (42 of 486) had wheezing at presentation. In a follow-up study of patients who visited two or more times after discharge, 13 (including 5 cases of RWE) of 21 MP pneumonia patients with initial wheezing and 25 (including 2 cases of RWE) of 159 MP pneumonia patients without wheezing had at least one wheezing episode after discharge (table 2). Although not all patients were followed-up, it was estimated that at least 31 of the total MP pneumonia patients (n=501, 6.2%) showed a recurrent wheezing after initial MP infection.

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